Tackling drug-resistant infections globally: report and recommendations
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Following 19 months of consultation, this report sets out the Review on Antimicrobial Resistance’s final recommendations to tackle antimicrobial resistance (AMR) globally, as commissioned by sponsors, the UK Government and the Wellcome Trust.
C-reactive protein POCT to guide antibiotic prescribing in primary care settings for acute respiratory tract infections
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European Network for Health Technology Assessment (EUnetHTA), published online January 2019
This collaborative assessment on C-reactive protein (CRP) point-of-care testing (POCT) aims to guide antibiotic prescribing in primary care settings for acute respiratory tract infections (RTIs). The assessment sought to answer three questions by conducting three separate systematic reviews:
1. Does the use of CRP POCT in primary care lead to a significa...
Health Technology Assessment of CRP POCT to guide antibiotic prescribing for acute respiratory tract infections in primary care settings
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Health Information and Quality Authority (HIQA), published online April 2019
This health technology assessment (HTA) aimed to establish the clinical and cost-effectiveness of CRP POCT, plus examined the organisational implications of the potential introduction of the technology into primary care. A summary of key findings is provided below:
• Antimicrobial resistance is a growing and significant threat to public health
• It is widely recognised...
Impact of CRP POC testing in ambulatory care: a systematic review and meta-analysis
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Jan Verbakel, Joseph Lee, Clare Goyder, Pui San Tan, Thanusha Ananthakumar, Philip Turner, Gail Hayward, and Ann Van den Bruel
BMJ Open, 2019
The aim of this review was to collate all available evidence on the impact of C-reactive protein (CRP) point-of-care testing (POCT) on patient-relevant outcomes in children and adults in ambulatory care.
A total of 11 randomised controlled trials and 8 nonrandomised controlled studies were included, report...