Eun Hee Nah, Seon Cho, Suyoung Kim, Han Ik Cho
Ann Lab Med. 2017;37(1):28-33.
In this study, the authors evaluated the clinical value of a point-of-care test (POCT) for measuring the urinary albumin-creatinine ratio (ACR) in prediabetes and diabetes. The group obtained spot urine samples from 226 prediabetic and 275 diabetic individuals during regular health checkups and measured urinary ACR by using point-of-care and laboratory quantitative tests.
The study found that the positive rates of albuminuria measured by the ACR POCT were 15.5% in prediabetes and 30.5% in diabetes. In the prediabetic population, the sensitivity, specificity, positive predictive value, negative predictive value, and overall accuracy of the POCT were 92.0%, 94.0%, 65.7%, 99.0% and 93.8%, respectively; the corresponding values in the diabetic population were 80.0%, 91.6%, 81.0%, 91.1%, and 88.0%, respectively. The median ACR values in the point-of-care tests for measurement ranges of <30, 30-300 and >300 mg/g were 9.4, 46.9 and 368.8 mg/g, respectively, using the laboratory method.
The authors conclude that the ACR point-of-care test demonstrated high sensitivity, specificity and negative predictive value. This suggests that the test can be used to screen for albuminuria in cases of prediabetes and diabetes.
The full publication can be accessed here.
© 2023 Abt. Alle Rechte vorbehalten. Alle genannten Marken sind Marken der Abbott-Unternehmensgruppe oder ihrer jeweiligen Eigentümer.
The American Diabetes Association standards of care - 2023 guidelines provide recommendations for healthcare providers regarding cardiovascular disease (CVD) and risk management in people with diabetes. The authors highlight that atherosclerotic cardiovascular disease (ASCVD) and heart failure (HF) are leading causes of morbidity and mortality for people with diabetes, noting that simultaneously addressing cardiovascular (CV) risk factors can con...
American Diabetes Association recommendations for cardiovascular disease in diabetesenMehr Erfahren
The Kidney Disease: Improving Global Outcomes (KIDGO) 2022 clinical practice guidelines are based on a systematic review of evidence and aim to assist health care professionals with their decision making for people with diabetes and chronic kidney disease (CKD). The authors highlight that by 2045, 784 million people are estimated to have diabetes globally, of whom ≥40% will develop CKD, potentially leading to kidney failure requiring dialysis or ...
KIDGO clinical practice guidelines: diabetes management in chronic kidney diseaseenMehr Erfahren
The objective of this longitudinal cohort study was to determine the prevalence of chronic kidney disease (CKD) and associated risk factors in a rural South African population. The authors note that infectious and non-communicable disease are a substantial risk for CKD in Africa, but that heterogeneity in assessment and diagnostic criteria hamper the interpretation of prevalence.
Chronic kidney disease prevalence and risks in rural South AfricaenMehr Erfahren