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Dramatic Increases of Dengue Cases Around the World: Lessons Learned from Brazil, Bangladesh, and Sri Lanka

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Presentations

  • Dr. Mauricio Nogueira, Associate Professor

    Dr. Mauricio Nogueira, Associate Professor
    (Brazil)
    Speaker

    Dengue and Chikungunya Outbreaks in Brazil (2024)


    Laboratório de Pesquisas em Virologia

    Faculdade de Medicina de São José do Rio Preto

    Mauricio Nogueira is a Professor of Microbiology and Infectious Diseases at Faculdade de Medicina de SJ Rio Preto (FAMERP) in Brazil. He received a MD and a PhD from Federal University of Minas Gerais and then completed a postdoctoral training at NIAID, Bethesda. He is currently Chair of ACAV/ASTMH and is an associate adjunct professor at Department of Pathology, University of Texas Medical Branch.

  • Dr. Mohammad Shafiul Alam, Scientist, Enteric and Respiratory Infections

    Dr. Mohammad Shafiul Alam, Scientist, Enteric and Respiratory Infections
    (Bangladesh)
    Speaker

    The 2023 Dengue Surge in Bangladesh: Impact of Dengue Serotype 2 Resurgence


    Infectious Diseases Division

    icddr,b

    Mohammad Shafiul Alam, a Scientist with a PhD in Parasitology, leads the Parasitic and Vector-borne Infections Unit of the Infectious Diseases Division at icddr,b. He has received advanced training in point-of-care diagnostics from leading institutions, including the University of Tokyo, Fondation Mérieux, PATH, and the University of Washington. Recently, he has been involved in NIH-sponsored dengue vaccine trials in Bangladesh. Additionally, Dr. Alam is conducting multiple studies on the epidemiology and diagnostic evaluation of arbovirus transmission in Bangladesh.

  • Dr. Neelika Malavige, Professor, Department of Immunology and Molecular Medicine

    Dr. Neelika Malavige, Professor, Department of Immunology and Molecular Medicine
    (Sri Lanka)
    Speaker

    Evolution of the Dengue Virus: Why it Matters for Diagnostics (and Vaccines)?


    University of Sri Jayewardenepura

    Neelika Malavige is a Professor at the Department of Immunology and Molecular Medicine, University of Sri Jayewardenepura, Sri Lanka and an academic visitor at the Weatherall Institute of Molecular Medicine, University of Oxford. She is a member of the Executive Committee of the International Society of Infectious Diseases and a member of many national committees and technical advisory committees on dengue control, communicable diseases, and vaccines in Sri Lanka. Her research focus has been on immunopathogenesis of dengue, biomarkers and immune correlates of protection and translating these findings into clinical trials.


The views and opinions presented are of the authors only. The content contained in this webcast is intended for informational / educational purposes only.

Background

Recent increases in dengue have made it one of the leading emerging mosquito-transmitted flavivirus. Rapid global spread of dengue is associated with higher population density, climate change, an increase in frequency of travel into endemic areas, among other factors. According to estimations from Brazil’s Ministry of Health, approximately 6 million cases of dengue were suspected in the first half of 2024. Nearly 56,000 cases were registered in the first 15 days of 2024 compared to 26,801 cases during the same period in 2023, an increase of 108%. As reported in a recent publication, the Resurgence of Dengue Virus Serotype 2, Bangladesh, in 2023, experienced the largest and most deadly dengue outbreak since the virus reemerged two decades ago. In Sri Lanka, scientific evidence showed two co-circulating genotypes of dengue virus serotype 3 (I and III) were responsible for large dengue outbreaks in the country where genotype I was not detected by certain PCR primers.

Join this global webinar for insights from regional experts on this growing and challenging epidemic in endemic areas.

Learning Objectives

  • Examine dengue epidemiology and in-country impact with re-introduction of dengue serotypes.
  • Describe societal, logistical and technical challenges associated with the diagnosis of dengue.
  • Summarize evidence and strategies to detect and control infection.
  • Discuss the impact of genotypic variation on dengue diagnosis.

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